Ana kiran HPMC a matsayin hydroxypropyl methylcellulose.
Samfurin HPMC yana zaɓar cellulose auduga mai tsafta a matsayin albarkatun ƙasa kuma an yi shi ta hanyar etherification na musamman a ƙarƙashin yanayin alkaline. An kammala dukkan tsari a ƙarƙashin yanayin GMP da saka idanu ta atomatik, ba tare da wani kayan aiki mai aiki kamar sassan dabba da maiko ba.
Kaddarorin HPMC:
HPMC samfurin ne ba ionic cellulose ether, bayyanar ne fari foda, wari m, mai narkewa a cikin ruwa da kuma mafi iyakacin duniya Organic kaushi (kamar dichloroethane) da kuma dace rabo na ethanol / ruwa, propyl barasa / ruwa, da dai sauransu Aqueous bayani yana da surface aiki, high nuna gaskiya da kuma barga yi. HPMC yana da kaddarorin gel na thermal, samfurin ruwan samfurin yana mai zafi don samar da hazo gel, sannan narkar da bayan sanyaya, ƙayyadaddun ƙayyadaddun ƙayyadaddun samfuran gel ɗin sun bambanta. Solubility canje-canje tare da danko, ƙananan danko, mafi girma da solubility, daban-daban bayani dalla-dalla na HPMC yana da wani bambanci a cikin kaddarorin, HPMC a cikin ruwa ba ya shafar PH darajar. Girman barbashi: 100 raga izinin wucewa ya fi 100%. Girman girma: 0.25-0.70g/ (yawanci game da 0.5g/), ƙayyadaddun nauyi 1.26-1.31. Yanayin zafin jiki: 190-200 ℃, carbonization zafin jiki: 280-300 ℃. Tashin hankali: 42-56dyn/cm a cikin 2% bayani mai ruwa. Tare da karuwar abun ciki na methoxyl, ma'anar gel ta ragu, ƙarancin ruwa ya karu, kuma aikin saman ya karu. HPMC yana da halaye na thickening, salting, low ash abun ciki, PH kwanciyar hankali, ruwa riƙewa, girma da kwanciyar hankali, m film kafa da kuma m juriya ga enzyme, tarwatsa da cohesiveness.
Aikace-aikacen HPMC:
1. Tablet shafi: HPMC amfani da matsayin fim shafi abu a cikin m shirye-shirye, zai iya samar da m, santsi da kyau film, da taro taro na 2% -8%. Bayan shafi, kwanciyar hankali na wakili zuwa haske, zafi da zafi yana ƙaruwa; Mara ɗanɗano da wari, mai sauƙin ɗauka, da pigment na HPMC, allon rana, man shafawa da sauran ingantaccen kayan aiki. Shafi na yau da kullun: ruwa ko 30-80% ethanol don narkar da HPMC, tare da 3-6% bayani, ƙara ƙarin kayan aiki (kamar: zafin ƙasa -80, man castor, PEG400, talc, da sauransu).
2. Enteric-mai narkewa shafi kadaici Layer: a saman Allunan da granules, HPMC shafi da aka fara amfani da matsayin kasa shafi kadaici Layer, sa'an nan kuma mai rufi da Layer na HPMCP enteric-mai narkewa abu. HPMC fim iya inganta kwanciyar hankali na enteric-mai narkewa shafi wakili a cikin ajiya.
3. Tsare-tsare-tsari: ta yin amfani da HPMC a matsayin wakili mai haifar da pore da kuma dogara ga ethyl cellulose a matsayin kayan kwarangwal, ana iya yin allunan da aka dade-saki.
4. Thickening wakili da colloid m m da ido saukad: HPMC for thickening wakili fiye amfani da taro na 0.45-1%.
5. Adhesive: HPMC a matsayin mai ɗaure babban taro na 2% -5%, ana amfani dashi don inganta kwanciyar hankali na manne hydrophobic, yawan amfani da taro na 0.5-1.5%.
6. Wakilin jinkiri, mai sarrafawa mai sarrafawa da wakili na dakatarwa. Wakilin dakatarwa: adadin da aka saba na wakilin dakatarwa shine 0.5-1.5%.
7. Abinci: HPMC a matsayin thickening wakili kara zuwa iri-iri na sha, kiwo kayayyakin, condiments, sinadirai masu abinci, kamar yadda thickening wakili, dauri, emulsifier, dakatar wakili, stabilizer, ruwa riƙewa wakili, excifer, da dai sauransu.
8. Ana amfani da su a cikin kayan kwalliya kamar adhesives, emulsifiers, masu samar da fim, da sauransu.
Lokacin aikawa: Janairu-14-2022