Hydroxypropyl methylcellulose (HPMC) polymer ne mai dacewa kuma ana amfani dashi sosai a masana'antu daban-daban, sananne don kaddarorin sa da aikace-aikace na musamman. Wannan fili ya samo asali ne daga cellulose, polymer na halitta da ake samu a ganuwar tantanin halitta. Don fahimtar abun da ke ciki na hydroxypropylmethylcellulose, ya zama dole don zurfafa cikin tsari da haɗin wannan abin da aka samu na cellulose.
Tsarin cellulose:
Cellulose wani hadadden carbohydrate ne wanda ya ƙunshi layin layi na raka'a β-D-glucose mai alaƙa da haɗin gwiwar β-1,4-glycosidic. Waɗannan sarƙoƙin glucose ana haɗa su ta hanyar haɗin gwiwar hydrogen don samar da tsayayyen tsari mai tsauri. Cellulose shine babban tsarin tsarin ganuwar tantanin halitta, yana ba da ƙarfi da ƙarfi ga ƙwayoyin shuka.
Abubuwan da aka samo daga Hydroxypropyl Methylcellulose:
Hydroxypropyl methylcellulose an haɗa shi ta hanyar canza cellulose ta hanyar sinadarai da gabatar da hydroxypropyl da ƙungiyoyin methyl cikin babban sarkar cellulose. Samfura yawanci ya haɗa da matakai masu zuwa:
Halin etherification:
Methylation: Yin maganin cellulose tare da maganin alkaline da methyl chloride don gabatar da kungiyoyin methyl (-CH3) a cikin kungiyoyin hydroxyl (-OH) na cellulose.
Hydroxypropylation: Methylated cellulose ya kara amsawa tare da propylene oxide don gabatar da ƙungiyoyin hydroxypropyl (-CH2CHOHCH3) a cikin tsarin cellulose. Wannan tsari yana inganta narkewar ruwa kuma yana canza yanayin jiki na cellulose.
tsarkakewa:
Sa'an nan kuma ana tsabtace cellulose da aka gyara don cire duk wani reagents, samfurori ko ƙazanta waɗanda ba a yi su ba.
Bushewa da niƙa:
An bushe hydroxypropyl methylcellulose mai tsabta kuma an yi shi a cikin foda mai kyau wanda aka shirya don amfani a aikace-aikace iri-iri.
Sinadaran na Hydroxypropyl Methylcellulose:
Abun da ke tattare da hydroxypropyl methylcellulose yana da alaƙa da matakin maye gurbin, wanda ke nufin matakin da hydroxypropyl da ƙungiyoyin methyl ke maye gurbin ƙungiyoyin hydroxyl a cikin sarkar cellulose. Maki daban-daban na HPMC suna da digiri daban-daban na maye gurbinsu, suna shafar solubility, danko da sauran kaddarorin.
Za a iya bayyana ma'anar sinadarai na hydroxypropyl methylcellulose a matsayin (C6H7O2(OH) 3-mn (OCH3) m (OCH2CH (OH) CH3) n) _x, inda m da n suna wakiltar matakin maye gurbin.
m: digiri na methylation (ƙungiyoyin methyl da rukunin glucose)
n: digiri na hydroxypropylation (rukunin hydroxypropyl kowace rukunin glucose)
x: adadin raka'o'in glucose a cikin sarkar cellulose
Fasaloli da Aikace-aikace:
Solubility: HPMC ruwa ne mai narkewa, kuma matakin maye gurbin yana shafar halayen solubility. Yana samar da bayani mai haske da danko a cikin ruwa, yana sa ya dace da nau'i-nau'i iri-iri.
Dankowa: Dankowar maganin HPMC ya dogara da abubuwa kamar nauyin kwayoyin halitta da digiri na maye gurbin. Wannan kadarar tana da mahimmanci ga aikace-aikace kamar magunguna waɗanda ke buƙatar tsarin sarrafawa mai sarrafawa.
Samar da Fim: HPMC na iya ƙirƙirar fina-finai na bakin ciki yayin da maganin ya bushe, yana sa ya zama mai amfani a cikin sutura a cikin magunguna, abinci da sauran masana'antu.
Stabilizers and Thickeners: A cikin masana'antar abinci, ana amfani da HPMC azaman mai kauri da daidaitawa a cikin kayayyaki iri-iri, gami da miya, kayan zaki, da kayan gasa.
Aikace-aikacen Magunguna: Ana amfani da HPMC sosai a cikin ƙirar magunguna, gami da allunan, capsules, da hanyoyin maganin ido, saboda kaddarorin sakin sa na sarrafawa da daidaituwar halittu.
Gine-gine da sutura: Ana amfani da HPMC a cikin kayan gini kamar turmi, tile adhesives da plasters. Hakanan ana amfani dashi azaman mai kauri da stabilizer a cikin zane-zane da fenti.
Kayayyakin Kulawa na Keɓaɓɓu: A cikin masana'antar kayan kwalliya da masana'antar kulawa, ana samun HPMC a cikin samfuran kamar su creams, lotions da shampoos, inda yake ba da laushi da kwanciyar hankali.
Ana samun Hydroxypropyl methylcellulose ta hanyar methylation da hydroxypropylation na cellulose. Polymer-manufafi ne mai fa'ida mai fa'ida. Kaddarorinsa na musamman sun sa ya zama mai daraja a masana'antu kamar su magunguna, abinci, gini da kulawa na sirri. Sarrafa gyare-gyare na cellulose na iya daidaita kaddarorin HPMC, yana mai da shi muhimmin sashi na samfuran da yawa da muke fuskanta a rayuwarmu ta yau da kullun.
Lokacin aikawa: Janairu-10-2024