Hydroxypropyl Methyl Cellulose (HPMC), wanda kuma aka sani da sunan kasuwanci hypromellose, polymer roba ne da aka samu daga cellulose na halitta. Babban tushen cellulose don samar da HPMC shine yawanci ɓangaren itace ko auduga. Tsarin masana'antu ya haɗa da canza sinadarai ta hanyar etherification, gabatar da hydroxypropyl da ƙungiyoyin methyl akan kashin bayan cellulose.

Samar da HPMC ya ƙunshi matakai da yawa:

1. Ciwon Cellulose:
   • Ana samun cellulose daga tushen shuka, da farko ɓangaren itace ko auduga. Ana fitar da cellulose kuma an tsarkake shi don samar da ɓangaren litattafan almara.
2. Alkalization:
   • Ana kula da ɓangaren litattafan cellulose tare da maganin alkaline, yawanci sodium hydroxide (NaOH), don kunna ƙungiyoyin hydroxyl akan sarkar cellulose.
3. Etherification:
   • Etherification shine babban mataki a cikin samar da HPMC. Ana amsa cellulose alkalized tare da propylene oxide (na ƙungiyoyin hydroxypropyl) da methyl chloride (na ƙungiyoyin methyl) don gabatar da waɗannan rukunin ether akan kashin bayan cellulose.
4. Neuralization da Wankewa:
   • Sakamakon gyare-gyaren cellulose, wanda yanzu shine Hydroxypropyl Methyl Cellulose, yana jurewa tsari don cire duk wani alkali da ya rage. Sa'an nan kuma a wanke shi sosai don kawar da ƙazanta da samfurori.
5. Bushewa da Niƙa:
   • An bushe cellulose da aka gyara don cire danshi mai yawa sannan a niƙa a cikin foda mai kyau. Ana iya sarrafa girman barbashi bisa ga aikace-aikacen da aka yi niyya.

Samfurin HPMC da aka samu shine fari ko fari-fari tare da nau'ikan nau'ikan hydroxypropyl da maye gurbin methyl. Takamaiman kaddarorin HPMC, kamar su solubility, danko, da sauran halayen aiki, sun dogara da matakin maye gurbin da tsarin masana'anta.

Yana da mahimmanci a lura cewa HPMC shine polymer Semi-synthetic, kuma yayin da aka samo shi daga cellulose na halitta, yana fuskantar gyare-gyaren sinadarai masu mahimmanci yayin aikin masana'antu don cimma kaddarorin da ake so don aikace-aikacen masana'antu daban-daban.