Shiri Hydroxypropyl Methylcellulose (HPMC) shafi bayani ne na asali tsari a Pharmaceutical da kuma abinci masana'antu.HPMC shine polymer da aka saba amfani dashi a cikin abubuwan da aka shafa saboda kyawawan abubuwan ƙirƙirar fina-finai, kwanciyar hankali, da dacewa tare da kayan aiki daban-daban.Ana amfani da mafita mai rufi don ba da yadudduka masu kariya, sarrafa bayanan martaba, da haɓaka bayyanar da ayyuka na allunan, capsules, da sauran tsayayyen nau'ikan sashi.
1. Abubuwan da ake buƙata:
Hydroxypropyl Methylcellulose (HPMC)
Narke (yawanci ruwa ko cakuda ruwa da barasa)
Plasticizer (na zaɓi, don inganta sassaucin fim ɗin)
Sauran additives (na zaɓi, kamar masu canza launi, opacifiers, ko jami'an anti-tacking)
2. Kayan aiki da ake buƙata:
Cakuda jirgin ruwa ko akwati
Stirrer (kanikanci ko Magnetic)
Ma'aunin nauyi
Tushen dumama (idan an buƙata)
Sieve (idan ya cancanta don cire lumps)
pH mita (idan pH daidaitawa ya zama dole)
Kayan kariya (safofin hannu, tabarau, rigar lab)
3. Tsari:
Mataki 1: Auna Sinadaran
Auna adadin da ake buƙata na HPMC ta amfani da ma'aunin awo.Adadin na iya bambanta dangane da abubuwan da ake so na maganin shafi da girman nau'in.
Idan ana amfani da filastik ko wasu abubuwan ƙari, auna adadin da ake buƙata kuma.
Mataki na 2: Shirye-shiryen Magani
Ƙayyade nau'in sauran ƙarfi da za a yi amfani da su dangane da aikace-aikacen da dacewa tare da sinadaran aiki.
Idan ana amfani da ruwa azaman sauran ƙarfi, tabbatar yana da tsafta kuma zai fi dacewa distilled ko an cire shi.
Idan amfani da cakuda ruwa da barasa, ƙayyade rabo mai dacewa dangane da solubility na HPMC da halayen da ake so na maganin shafi.
Mataki na 3: Hadawa
Sanya jirgin ruwan cakuda akan mai motsawa kuma ƙara sauran ƙarfi.
Fara motsawa da sauran ƙarfi a matsakaicin matsakaici.
Sannu a hankali ƙara foda HPMC da aka riga aka auna a cikin kaushi mai motsawa don guje wa ƙullewa.
Ci gaba da motsawa har sai an tarwatsa foda na HPMC daidai a cikin sauran ƙarfi.Wannan tsari na iya ɗaukar ɗan lokaci, ya danganta da ƙaddamarwar HPMC da ingancin kayan aikin motsa jiki.
Mataki na 4: dumama (idan an buƙata)
Idan HPMC bai narke gaba ɗaya a cikin zafin jiki ba, dumama mai laushi na iya zama dole.
Haɗa cakuda yayin motsawa har sai HPMC ta narkar da gaba ɗaya.Yi hankali kada a yi zafi, saboda yawan zafin jiki na iya lalata HPMC ko wasu abubuwan da ke cikin maganin.
Mataki na 5: Ƙara Plasticizer da Sauran Abubuwan Haɗi (idan an zartar)
Idan kuna amfani da filastik, ƙara shi zuwa bayani a hankali yayin motsawa.
Hakazalika, ƙara duk wasu abubuwan da ake so kamar masu canza launin ko mai gani a wannan matakin.
Mataki na 6: Daidaita pH (idan ya cancanta)
Bincika pH na maganin shafawa ta amfani da mita pH.
Idan pH ya fita daga kewayon da ake so don kwanciyar hankali ko dalilai masu dacewa, daidaita shi ta ƙara ƙananan adadin acidic ko mafita na asali daidai.
Dama bayani sosai bayan kowane ƙari kuma sake duba pH har sai an cimma matakin da ake so.
Mataki na 7: Haɗin Ƙarshe da Gwaji
Da zarar an ƙara duk abubuwan da aka haɗa kuma an haɗa su sosai, ci gaba da motsawa na ƴan mintuna kaɗan don tabbatar da kamanni.
Yi kowane ingantattun gwaje-gwaje masu mahimmanci kamar ma'aunin danko ko duban gani don kowane alamun ɓarna ko rabuwar lokaci.
Idan ana buƙata, a wuce maganin ta hanyar sieve don cire duk wani ƙullun da ba a narkar da shi ba.
Mataki 8: Adana da Marufi
Canja wurin maganin murfin HPMC da aka shirya cikin kwantena masu dacewa, zai fi dacewa kwalabe gilashin amber ko kwantena filastik masu inganci.
Yi lakabin kwantena tare da mahimman bayanai kamar lambar tsari, ranar shiri, maida hankali, da yanayin ajiya.
Ajiye maganin a wuri mai sanyi, busasshen da aka kiyaye shi daga haske da danshi don kiyaye kwanciyar hankali da rayuwar sa.
4. Nasiha da Tunani:
Koyaushe bi kyawawan ayyukan dakin gwaje-gwaje da jagororin aminci lokacin sarrafa sinadarai da kayan aiki.
Kula da tsabta da haifuwa a duk lokacin shirye-shiryen don guje wa gurɓatawa.
Gwada dacewa da maganin shafa tare da abin da aka yi niyya (Allunan, capsules) kafin aikace-aikacen babban sikelin.
Gudanar da karatun kwanciyar hankali don tantance aikin dogon lokaci da yanayin ajiya na maganin sutura.
Yi rikodin tsarin shirye-shiryen kuma adana bayanan don dalilai na sarrafa inganci da bin ka'idoji.
Lokacin aikawa: Maris-07-2024