Domin kwatanta CMC (carboxymethylcellulose) da HPMC (hydroxypropylmethylcellulose), muna buƙatar fahimtar kaddarorin su, aikace-aikace, fa'idodi, rashin amfani, da yuwuwar amfani da lokuta.Dukkan abubuwan da aka samu na cellulose ana amfani dasu sosai a masana'antu daban-daban, gami da magunguna, abinci, kayan kwalliya da gini.Kowannensu yana da kaddarorin musamman waɗanda suka sa su dace da dalilai daban-daban.Bari mu yi cikakken kwatanci mai zurfi don ganin wanda ya fi kyau a yanayi daban-daban.
1. Ma'ana da tsari:
CMC (carboxymethylcellulose): CMC shine asalin cellulose mai narkewa da ruwa wanda aka samar ta hanyar amsawar cellulose da chloroacetic acid.Ya ƙunshi ƙungiyoyin carboxymethyl (-CH2-COOH) waɗanda ke haɗe da wasu ƙungiyoyin hydroxyl na glucopyranose monomers waɗanda ke yin kashin bayan cellulose.
HPMC (hydroxypropyl methylcellulose): HPMC kuma wani nau'in cellulose mai narkewa ne wanda aka samar ta hanyar magance cellulose tare da propylene oxide da methyl chloride.Ya ƙunshi hydroxypropyl da ƙungiyoyin methoxy waɗanda ke haɗe zuwa kashin bayan cellulose.
2. Solubility:
CMC: Sosai mai narkewa a cikin ruwa, samar da wani m, danko bayani.Yana nuna halin kwararar pseudoplastic, wanda ke nufin cewa danko yana raguwa a ƙarƙashin damuwa mai ƙarfi.
HPMC: Hakanan mai narkewa a cikin ruwa, yana samar da maganin ɗan danko fiye da CMC.Hakanan yana nuna halayen pseudoplastic.
3.Hanyoyin Rheological:
CMC: Yana Nuna halin ɓacin rai, wanda ke nufin cewa ɗanƙoƙin sa yana raguwa tare da ƙara yawan juzu'i.Wannan kadarar ta sa ta dace da aikace-aikace inda ake buƙatar kauri amma maganin yana buƙatar gudana cikin sauƙi a ƙarƙashin shear, kamar fenti, wanki da magunguna.
HPMC: yana nuna irin wannan hali na rheological zuwa CMC, amma dankon sa gabaɗaya ya fi girma a ƙananan ƙima.Yana da mafi kyawun kayan aikin fim, yana sa ya dace da aikace-aikace kamar su sutura, adhesives da tsarin sarrafawa-saki magunguna.
4. Kwanciyar hankali:
CMC: Gabaɗaya tsayayye akan kewayon pH da zazzabi.Yana iya jure wa matsakaicin matakan electrolytes.
HPMC: Mafi kwanciyar hankali fiye da CMC a ƙarƙashin yanayi na acidic, amma yana iya sha hydrolysis a ƙarƙashin yanayin alkaline.Hakanan yana kula da cations na divalent, wanda zai iya haifar da gelation ko hazo.
5. Aikace-aikace:
CMC: ana amfani da shi sosai azaman thickener, stabilizer da wakili mai riƙe ruwa a cikin abinci (kamar ice cream, miya), magunguna (kamar allunan, dakatarwa) da masana'antu (kamar cream, lotion) masana'antu.
HPMC: Yawanci ana amfani da su a cikin kayan gini (misali, mannen tayal siminti, filasta, turmi), magunguna (misali, allunan da za a iya sarrafawa, shirye-shiryen ido), da kayan kwalliya (misali, digon ido, kayayyakin kula da fata).
6. Guba da aminci:
CMC: Gabaɗaya an san shi azaman mai aminci (GRAS) ta hukumomin gudanarwa lokacin amfani da ƙayyadaddun iyaka a cikin aikace-aikacen abinci da magunguna.Yana da biodegradable kuma ba mai guba ba.
HPMC: Hakanan ana ɗaukar lafiya don amfani a cikin iyakokin da aka ba da shawarar.Yana da jituwa kuma ana amfani dashi ko'ina a cikin filin harhada magunguna azaman wakili mai sarrafawa da mai ɗaure kwamfutar hannu.
7. Farashin da Samuwar:
CMC: Yawanci ya fi HPMC tasiri.Ana samun sauƙin samuwa daga masu kaya daban-daban a duniya.
HPMC: Ya fi tsada kaɗan saboda tsarin samar da shi kuma wani lokacin ƙayyadaddun wadata daga wasu masu kaya.
8. Tasirin muhalli:
CMC: Biodegradable, wanda aka samo daga albarkatu masu sabuntawa (cellulose).Ana la'akari da yanayin muhalli.
HPMC: Har ila yau, ba za a iya cirewa ba kuma an samo shi daga cellulose, haka ma yana da mutuƙar muhalli.
Dukansu CMC da HPMC suna da ƙayyadaddun kaddarorin da ke sanya su ƙari mai mahimmanci a cikin masana'antu da yawa.Zaɓin tsakanin su ya dogara da ƙayyadaddun buƙatun aikace-aikacen kamar su solubility, danko, kwanciyar hankali da la'akari da farashi.Gabaɗaya, ana iya fifita CMC saboda ƙarancin farashinsa, faɗin kwanciyar hankali na pH, da dacewa don aikace-aikacen abinci da kayan kwalliya.HPMC, a gefe guda, ana iya fifita shi don mafi girman danko, ingantattun kaddarorin shirya fim, da aikace-aikace a cikin magunguna da kayan gini.A ƙarshe, zaɓi ya kamata ya dogara ne akan cikakken la'akari da waɗannan abubuwan da kuma dacewa da abin da aka yi niyya.
Lokacin aikawa: Fabrairu-21-2024